The Dow University of Health Sciences
The Dow University of Health Sciences (initials: DUHS), is one of the oldest public sector universities in Pakistan. The university comprises two leading health sciences undergraduate research institutes
About Dow University of Health Sciences
Dow International Medical College and Dow Medical College. The University also has a very strong department of Postgraduate studies which monitors various basic medical sciences and clinical sciences programs at DUHS. Established in 1945, it is known for its strong emphasis on economics, biomedical, health, and medical research programs. The institution offers undergraduate, post-graduate and doctoral programs in almost all academic disciplines relating to medical sciences
The Problem that Got Them Thinking
Breast cancer is the leading cause of mortality among women. Every fifth breast cancer patient is diagnosed with HER2 positive breast cancer, which is a very aggressive type of cancer and thus requires timely and accurate diagnosis to limit the chances of mortality. Fluorescence in Situ Hybridization (FISH) test is the most commonly used method for the detection of HER2 Positive breast cancer. However, the process is quite tedious, consumes time and cannot be performed without highly trained practitioners.
The Value Delivered By Folio3 Digital Health
Folio3 played an important role in developing an IPad application targeting scientists and lab technicians to help in automating the whole process they follow for doing various practical’s in laboratories and pharmacies. The benchmark was an existing web application of the client which we need to replicate in an IOS application with new designs and minor functional changes. Application of such domains are not much available on IPad that’s why we may consider this one of a kind solution
This brings Us To Our Solution — Taking The Challenges Head-On
Contrast Enhancement is crucial in image processing, revealing information within low dynamic ranges. It improves image quality by enabling operations like contrast enhancement and noise reduction.
Image Binarization for segmentation, converts pixel images to binary. The ISO Data Algorithm sets an adaptive threshold by counting tone appearances to find an optimal center.
Spot Counting represents a cell's 'cytokine signature,' with diffusion creating a densely colored center fading to the edges. Spot size/color intensity indicates the released cytokine amount.
Cell Segmentation yields segments covering the entire image or extracted contours. Pixels within a region share similarities in color, intensity, or texture.
The Impact
Thanks to Folio3 and our partner Fidel AI’s expert team for developing the solution of Breast Cancer HER2 identification. Our client has been able to substantially improve the efficiency and accuracy of their HER2 identification process while enabling the practitioners to digitize and store the images for later usage.
Technologies used:
- Scikit-image
- Matlab+Java for the application.